Vitamin D Deficiency: The Unrecognized Cause of Flank Pain

A rare cause of flank pain

Urinary tract rupture is often complicated by septic shock and has a high mortality rate. Although it rarely represents a diagnostic challenge, a spontaneous rupture with urinary extravasation is a rare event which, when associated with strange and confounding clinical presentation, may rapidly evolve into life threatening septic shock. A 70-year-old patient presented with intense right leg and...

Vitamin D deficiency and stroke

Vitamin D comprises a group of fat-soluble pro-hormones, obtained from sun exposure, food, and supplements, and it must undergo two hydroxylation reactions to be activated in the body. Several studies have shown the role of vitamin D in mineral metabolism regulation, especially calcium, phosphorus, and bone metabolism. Some factors such as inadequate vitamin intake and liver or kidney disorders...

Vitamin D deficiency: consequence or cause of CKD?

Pioneering studies in the 1970s demonstrated that CKD leads to substantial perturbations in the vitamin D endocrine system and, as a result, bone loss (1–4). In particular, in CKD, renal production of 1,25-dihydroxyvitamin D (1,25(OH)2D) from 25hydroxyvitamin D (25(OH)D) is markedly reduced, leading to low circulating 1,25(OH)2D concentrations. Insufficient 1,25(OH)2D contributes to the develop...

The effect of vitamin D supplementation on the size of uterine leiomyoma in women with vitamin D deficiency

Vitamin D Deficiency and Pain: Clinical Evidence of Low Levels of Vitamin D and Supplementation in Chronic Pain States

INTRODUCTION A number of studies suggest a link between low levels of 25-hydroxy vitamin D and incidence of acute and chronic pain. Clinical studies of vitamin D supplementation in patients with known vitamin D deficiency have shown mixed results in improving pain scores. METHODS In this article, vitamin D deficiency risk factors are observed and adequate levels of 25-hydroxy vitamin D define...